
Tesamorelin is a stabilized analog of GHRH(1-44)—growth-hormone-releasing hormone—bearing an N-terminal modification that resists enzymatic degradation. Acting on the GHRH receptor of pituitary somatotrophs, it is studied for its ability to stimulate the body’s own pulsatile growth-hormone release and downstream IGF-1, and is particularly investigated for its influence on visceral adipose tissue and lipid metabolism—making it a compound of keen interest for researchers studying the GHRH–GH axis.

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