
SLU-PP-332 is a synthetic pan-agonist of the estrogen-related receptors (ERRα/β/γ, with preferential ERRα potency) studied as a so-called ‘exercise mimetic.’ It is investigated for its recruitment of the PGC-1α coactivator to drive mitochondrial biogenesis, fatty-acid oxidation, and the oxidative gene programs associated with endurance—activating an exercise-like metabolic response without physical exertion. This compound gives researchers a novel platform for exploring metabolic and performance-related signaling.

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